J Nat Prod 1991 Mar-Apr;54(2):453-9

Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa.

Aquino R, De Feo V, De Simone F, Pizza C, Cirino G.

Dipartimento di Chimica delle Sostanze Naturali, Universita degli Studi di Napoli Federico II, Italy.

Bioassay-directed fractionation of the anti-inflammatory extracts of Uncaria tomentosa, using the carrageenan-induced edema in rat paw, has led to the isolation of a new quinovic acid glycoside 7 as one of the active principles. Furthermore, a new triterpene 8 was isolated as its methyl ester. The structures were elucidated by spectral and chemical studies.