FULL TEXT VERSIONS REQUIRES ADOBE ACROBAT
SAMENTO (TOA-Free Cat's Claw)
Pentacyclic Alkaloid Type Uncaria tomentosa
NEW NutraNews: Pilot Study Reveals New Weapon Against
Lyme Borreliosis - A Disease Linked to Over 300 Medical Conditions. Oct 2003
Samento Overview / Compilation of five reports:
Samento in the Primary Care Setting, John Kule, M.D., British Naturopathic Journal,
Vol. 19, No. 2, Summer 2002
Randomized Double Blind Trial of an Extract from the Pentacyclic Alkaloid-Chemotype
of Uncaria tomentosa for the Treatment of Rheumatoid Arthritis, ERICH MUR, FRANK HARTIG,
GÜNTHER EIBL, and MICHAEL SCHIRMER, The Journal of Rheumatology 2002:29:4
Samento Treats Successfully Over 100 Diseases, Lechitel Weekly, Sofia, Bulgaria.
April 2003 (Most widely read Bulgarian medical publication).
Live Blood Analysis Report treatment of Rheumatoid Arthritis, Arthritis and Colon Cancer with
Samento, Professor Henk Oswald, M.D., PhD.
Pilot Study of Pentacyclic Alkaloid-Chemotype of Uncaria tomentosa for the treatment of
Lyme Disease presented at The International Symposium for Natural Treatment of Intracellular Micro Organism,
in Münich, Germany. (March 29, 2003)
CHARTS ONLY
TOA-Free Cat's Claw in the Primary Care Setting: John Kule, MD reports that 98% of patients treated with
rare Peruvian medicinal plant show clinical improvement: British Naturophathic Journal, June 2002
Pteropodine and isopteropodine positively modulate the function of rat muscarinic M1 and 5-HT2
receptors expressed in Xenopus oocyte: European Journal of Pharmacology, May 2002
Randomized Double Blind Trial of an Extract from the Pentacyclic Alkaloid-Chemotype
of Uncaria tomentosa for the Treatment of Rheumatoid Arthritis: Journal of Rheumatology, April 2002
Investigation of Una De Gato I. 7-Deoxyloganic acid and 15N NMR spectroscopic studies on pentacyclic
oxindole alkaloids from Uncaria tomentosa: Phytochemistry, July 2001
Two steroisomeric pentacyclic oxindole alkaloids from Uncaria tomentosa: uncarine C
and uncarine E: Acta Crystallographica, April 2001
Uncaria tomentosa (Willd.) D.C.: Cat's Claw, Uña de Gato, or Savéntaro:
The Journal of Alternative and Complementary Medicine, April 1999
Uncaria tomentosa (Willd.) DC.Ethnomedicinal use and new pharmacological, toxicological
and botanical results: Journal of Ethnopharmacology, January 1999
Pentacyclic oxindole alkaloids from Uncaria tomentosa induce human endothelial cells to release a
lymphocyte-proliferation-regulating factor: Planta Medica, December 1998
Cat's Claw
Uncaria tomentosa
Two New Nor-triterpene Glycosides from Peruvian “Uña de Gato” (Uncaria tomentosa):
Journal of Natural Products, February 2003
C-Med 100, a hot water extract of Uncaria tomentosa, prolongs lymphocyte survival in vivo:
Phytomedicine, January 2003
Biosynthesis of Sterols and Triterpenes in Cell Suspension Cultures of Uncaria tomentosa:
Plant Cell Physiology, December 2002
Synthesis and absolute configuration of a new 3,4-dihydro-beta-carboline-type alkaloid,
3,4-dehydro-5(S)-5-carboxystrictosidine, isolated from Peruvian Una de Gato (Uncaria tomentosa):
Chemical & Pharmaceutical Bulletin, October 2002
Anti-inflammatory activity of two different extracts of Uncaria tomentosa (Rubiaceae):
Journal of Ethnopharmacology, July 2002
Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis)
are independent of their alkaloid content: Phytomedicine, May 2002
Review of antiviral and immunomodulating properties of plants of the Peruvian rainforest with a
particular emphasis on Uña de Gato and Sangre de Grado: Alternative Medicine Review, December 2001
Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis: BMC Complimentary
and Alternative Medicine, December 2001
The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast
cancer cell line: Anti-cancer Research, August 2001
DNA repair enhancement of aqueous extracts of Uncaria tomentosa in a human volunteer study:
Phytomedicine, July 2001
Persistent response to pneumococcal vaccine in individuals supplemented with a novel water soluble
extract of Uncaria tomentosa, C-Med-100: Phytomedicine, July 2001
Improved method for the determination of oxindole alkaloids in Uncaria tomentosa by high performance
liquid chromatography: Planta Medica, July 2001
Vilcacora [Uncaria tomentosa (Willd.) DC. and Uncaria guianensis (Aublet) Gmell.] a review of published
scientific literature: Case Reports and Clinical Practice Review, February 2001
Effects of Uncaria tomentosa total alkaloid and its components on experimental amnesia in mice:
elucidation using the passive avoidance test: The Journal of Pharmacy and Pharmacology, December 2000
A new gluco indole alkaloid, 3, 4-dehydro-5-carboxystrictosidine, from Peruvian Una de Gato (Uncaria
tomentosa): Chemical & Pharmaceutical Bulletin, October 2000
Cat's claw inhibits TNFalpha production and scavenges free radicals- role in cytoprotection:
Free radical Biology & Medicine, July 2000
Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria
tomentosa: Phytomedicine, April 2000
Enhanced DNA repair, immune function and reduced toxicity of C-MED-100, a novel aqueous extract
from Uncaria tomentosa: Journal of Ethnopharmacology, February 2000
Stimulation of interleukin-1 and -6 production in alveolar macrophages by the neotropical liana,
Uncaria tomentosa (Uña de Gato): Journal of Ethnopharmacology, February 1999
Antiinflammatory actions of cat's claw- the role of NF-kappaB: Alimentary Pharmacology & Therapeutics,
December 1998
Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of
Uncaria tomentosa: Anti-cancer Research, October 1998
Evaluation of the In Vitro Antioxidant Activity in Extracts of Uncaria tomentosa (Willd.) DC.:
Phytotherapy Research, December 1997
Evaluation of the toxicity of Uncaria tomentosa by bioassays in vitro: Journal of Ethnopharmacology,
August 1997
Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts: Journal of Ethnopharmacology,
January 1993
Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa: Journal of Natural
Products, April 1991
New polyhydroxylated triterpenes from Uncaria tomentosa: Journal of Natural Products, June 1990
Plant metabolites. Structure and in vitro antiviral activity of quinovic acid glycosides from Uncaria
tomentosa and Guettarda platypoda: Journal of Natural Products, August 1989
Phytochemical and biological study of Uncaria tomentosa: Boll Soc Ital Biol Sper, June 1989
The alkaloids of Uncaria tomentosa and their phagocytosis-stimulating action: Planta Medica, October 1985